Pediatrics & Neonatology
Volume 49, Issue 4 , Pages 113-115 , August 2008

Enterovirus 71, One Virus and Many Stories

  • Shih-Min Wang

      Affiliations

    • Department of Emergency Medicine, National Cheng Kung University Medical College and Hospital, Tainan, Taiwan
    • ,
  • Tzong-Shiann Ho

      Affiliations

    • Department of Pediatrics, National Cheng Kung University Medical College and Hospital, Tainan, Taiwan
    • ,
  • Ching-Fen Shen

      Affiliations

    • Department of Pediatrics, National Cheng Kung University Medical College and Hospital, Tainan, Taiwan
    • ,
  • Ching-Chuan Liu

      Affiliations

    • Department of Pediatrics, National Cheng Kung University Medical College and Hospital, Tainan, Taiwan
    • Corresponding Author InformationCorresponding author. Department of Pediatrics, National Cheng Kung University Medical College and Hospital, 138 Sheng Li Road, Tainan 70428, Taiwan

Received 3 August 2008 ,Revised 27 August 2008 ,Accepted 28 August 2008.

References 

  1. Lum LC , Wong KT , Lam SK , et al.   Fatal enterovirus 71 encephalomyelitis . J Pediatr . 1998;133:795–798
  2. Wang SM , Liu CC , Tseng HW , et al.   Clinical spectrum of enterovirus 71 infection of children in southern Taiwan: emphasis on the neurological complications . Clin Infect Dis . 1999;29:184–190
  3. Liu CC , Tseng HW , Wang SM , Wang JR , Su IJ . An outbreak of enterovirus 71 infection in Taiwan, 1998: epidemiologic and clinical manifestations . J Clin Virol . 2000;17:23–30
  4. Huang CC , Liu CC , Chang YC , Chen CY , Wang ST , Yeh TF . Neurological complications in children with enterovirus 71 infection . N Engl J Med . 1999;341:936–942
  5. Lin TY , Chang LY , Hsia SH , et al.   The 1998 enterovirus 71 outbreak in Taiwan: pathogenesis and management . Clin Infect Dis . 2002;34(Suppl 2):S52–S57
  6. Wang SM , Lei HY , Su LY , et al.   Cerebrospinal fluid cytokines in various severity of enterovirus 71 brainstem encephalitis and echovirus meningitis . Clin Microbiol Infect . 2007;13:677–682
  7. Wang SM , Lei HY , Huang KJ , et al.   Pathogenesis of enterovirus 71 brainstem encephalitis in pediatric patients: the roles of cytokines and cellular immune activation in patients with pulmonary edema . J Infect Dis . 2003;188:564–570
  8. Wu JM , Wang JN , Tsai YC , et al.   Cardiopulmonary manifestations of fulminant enterovirus 71 infection . Pediatrics . 2002;109:e26
  9. Wang YF , Chou CT , Lei HY , et al.   A mouse-adapted enterovirus 71 strain causes neurological disease in mice after oral infection . J Virol . 2004;78:7916–7924
  10. Wang SM , Lei HY , Huang MC , et al.   Modulation of cytokine production by intravenous immunoglobulin in patients with enterovirus 71-associated brainstem encephalitis . J Clin Virol . 2006;37:47–52
  11. Huang MC , Wang SM , Hsu YW , Lin HC , Chi CY , Liu CC . Longterm cognitive and motor deficits after enterovirus 71 brainstem encephalitis in children . Pediatrics . 2006;118:e1785–e1788
  12. Wang SM , Lei HY , Huang MC , et al.   Therapeutic efficacy of milrinone in the management of enterovirus 71-induced pulmonary edema . Pediatr Pulmonol . 2005;39:219–223

PII: S1875-9572(08)60024-8

doi: 10.1016/S1875-9572(08)60024-8

Pediatrics & Neonatology
Volume 49, Issue 4 , Pages 113-115 , August 2008

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