Pediatrics & Neonatology
Volume 49, Issue 4 , Pages 141-144 , August 2008

Treatment with High-dose Methylprednisolone for Hepatic Veno-occlusive Disease in a Child with Rhabdomyosarcoma

  • I-Lun Chen

      Affiliations

    • Department of Pediatrics, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, Taiwan
    • ,
  • San-Nan Yang

      Affiliations

    • Department of Pediatrics and Graduate Institute of Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Taiwan
    • ,
  • Chih-Cheng Hsiao

      Affiliations

    • Department of Pediatrics, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, Taiwan
    • ,
  • Kuan-Sheng Wu

      Affiliations

    • Department of Pediatrics, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, Taiwan
    • ,
  • Jiunn-Ming Sheen

      Affiliations

    • Department of Pediatrics, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, Taiwan
    • Corresponding Author InformationCorresponding author. Department of Pediatrics, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Chang Gung University College of Medicine, 123 Ta-Pei Road, Niao-Sung Hsiang, Kaohsiung Hsien, Taiwan

Received 30 August 2007 ,Revised 26 February 2008 ,Accepted 28 August 2008.

References 

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  2. Kumar S , DeLeve LD , Kamath PS , Tefferi A . Hepatic venoocclusive disease (sinusoidal obstruction syndrome) after hematopoietic stem cell transplantation . Mayo Clin Proc . 2003;78:589–598
  3. Bearman SI . The syndrome of hepatic veno-occlusive disease after marrow transplantation . Blood . 1995;85:3005–3020
  4. Richardson P , Guinan E . The pathology, diagnosis, and treatment of hepatic veno-occlusive disease: current status and novel approaches . Br J Haematol . 1999;107:485–493
  5. DeLeve LD , Shulman HM , McDonald GB . Toxic injury to hepatic sinusoids: sinusoidal obstruction syndrome (venoocclusive disease) . Semin Liver Dis . 2002;22:27–41
  6. Bisogno G , de Kraker J , Weirich A , et al.   Veno-occlusive disease of the liver in children treated for Wilms tumor . Med Pediatr Oncol . 1997;29:245–251
  7. Bearman SI . Veno-occlusive disease of the liver . Curr Opin Oncol . 2000;12:103–109
  8. Jones RJ , Lee KSK , Beschorner WE , et al.   Venocclusive disease of the liver following bone marrow transplantation . Transplantation . 1987;44:778–783
  9. McDonald GB , Sharma P , Matthews DE , Shulman HM , Thomas ED . Venocclusive disease of the liver after bone marrow transplantation: diagnosis, incidence, and predisposing factors . Hepatology . 1984;4:116–122
  10. Arndt C , Hawkins D , Anderson JR , Breitfeld P , Womer R , Meyer W . Age is a risk factor for chemotherapy-induced hepatopathy with vincristine, dactinomycin, and cyclophosphamide . J Clin Oncol . 2004;22:1894–1901
  11. Goringe AP , Brown S , O'Callaghan U , et al.   Glutamine and vitamin E in the treatment of hepatic veno-occlusive disease following high-dose chemotherapy . Bone Marrow Transplant . 1998;21:829–832
  12. Richardson PG , Murakami C , Jin Z , et al.   Multi-institutional use of defibrotide in 88 patients after stem cell transplantation with severe veno-occlusive disease and multisystem organ failure: response without significant toxicity in a high-risk population and factors predictive of outcome . Blood . 2002;100:4337–4343
  13. Khoury H , Adkins D , Brown R , et al.   Does early treatment with high-dose methylprednisolone alter the course of hepatic regimen-related toxicity? . Bone Marrow Transplant . 2000;25:737–743
  14. Akyüz C , CaClar K , Emir S , Büyükpamukçu M . High-dose methylprednisolone treatment of hepatic veno-occlusive disease in a child with Wilms tumor . Pediatr Hematol Oncol . 2003;20:345–349
  15. Ortega JA , Donaldson SS , Ivy SP , Pappo A , Maurer HM . Venoocclusive disease of the liver after chemotherapy with vincristine, actinomycin D, and cyclophosphamide for treatment of rhabdomyosarcoma . Cancer . 1997;79:2435–2439

PII: S1875-9572(08)60029-7

doi: 10.1016/S1875-9572(08)60029-7

Pediatrics & Neonatology
Volume 49, Issue 4 , Pages 141-144 , August 2008

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