Pediatrics & Neonatology
Volume 49, Issue 6 , Pages 248-253, December 2008

Pneumococcal Osteomyelitis: Report of One Case

  • W. Luke Huang

      Affiliations

    • Department of Pediatrics, Mennonite Christian Hospital, Hualien, Taiwan
  • ,
  • Tse-Ming Wu

      Affiliations

    • Department of Radiology, Mennonite Christian Hospital, Hualien, Taiwan
    • Corresponding Author InformationCorresponding author. Department of Radiology, Mennonite Christian Hospital, 44 Min-Chuan Road, Hualien 970, Taiwan
  • ,
  • Chin-Kung Yu

      Affiliations

    • Department of Pediatrics, Mennonite Christian Hospital, Hualien, Taiwan
  • ,
  • Yung-Long Cheng

      Affiliations

    • Department of Pediatrics, Mennonite Christian Hospital, Hualien, Taiwan
  • ,
  • Chun Lien

      Affiliations

    • Department of Medical Research, Mennonite Christian Hospital, Hualien, Taiwan

Received 15 October 2007; received in revised form 6 August 2008; accepted 19 September 2008.

Article Outline

Acute osteomyelitis is uncommon in pediatric patients, affecting one in five thousand children younger than the age of thirteen. Bone infection caused by Streptococcus pneumoniae is extremely rare, accounting for only 1.3% of acute osteomyelitis in children. We report a case of penicillin-resistant Streptococcus pneumoniae-induced acute osteomyelitis in a 7-month-old male infant who was treated successfully with intravenous vancomycin and oral clindamycin.

Key Words:  anti-bacterial agents , osteomyelitis , Streptococcus pneumoniae

No full text is available. To read the body of this article, please view the PDF online.

 

Back to Article Outline

References 

  1. Ferroni A . Epidemiology and bacteriological diagnosis of paediatric acute osteoarticular infections . Arch Pediatr . 2007;14(Suppl 2):S91–S96
  2. Kocher MS , Lee B , Dolan M , et al.   Pediatric orthopedic infections: early detection and treatment . Pediatric Annal . 2006;35:112–122
  3. Kalouche I , Ghanem I , Kharrat K , Dagher F . Osteomyelitis of the rib due to Streptococcus pneumoniae: a very rare condition in children . J Pediatr Orthop B . 2005;14:55–60
  4. Moumlie K , Merckx J , Glorion C , et al.   Bacterial aetiology of acute osteoarticular infections in children . Acta Paediatrica . 2005;94:419–422
  5. Auh JS , Binns HJ , Katz BZ . Retrospective assessment of subacute or chronic osteomyelitis in children and young adults . Clin Pediatr . 2005;43:549–555
  6. Foo NH , Chen CT , Chow JC . Disseminated pneumococcal infection with pericarditis and cardiac tamponade: report of one case . Acta Paediatr Tw . 2005;46:301–304
  7. Eisentein EM , Gesundheit B . Neonatal hand abscess, osteomyelitis and meningitis caused by Streptopneumococcus pneumoniae . Pediatr Infect Dis J . 1998;17:76–81
  8. Bradley JS , Kaplan SL , Tan TQ , et al.   Pediatric pneumococcal bone and joint infections . Pediatrics . 1998;102:1376–1382
  9. Green M , Nyhan WL , Fousek MD . Acute hematogenous osteomyelitis . Pediatrics . 1956;17:368–382
  10. Paschlau G . Die besonderheiten der osteomyelitis im fruehen kindesalter . Monatschr Kinderheilkd . 1933;55:280–306 [In German]
  11. Green WT , Shannon JG . Osteomyelitis of infants: a disease different from osteomyelitis of older children . Arch Surg . 1936;32:462–493
  12. Blanche DW . Osteomyelitis of infants . J Bone Joint Surg [A] . 1952;34:71–85
  13. Self EB . Acute hematogenous osteomyelitis . Pediatrics . 1948;1:617–626
  14. Bunim JJ . Pneumococcal arthritis treated with penicillin: report of six cases . Med Clin North Am . 1946;30:584–596
  15. White M , Dennison WM . Acute hematogenous osteitis in childhood: review of 212 cases . J Bone & Joint Surg Br . 1952;34:608–623
  16. Edward MS , Baker CJ , Wagner ML , et al.   An etiologic shift in infantile osteomyelitis: the emergency of the group B streptococcus . J Pediatr . 1978;93:578–583
  17. Jacobs NM . Pneumococcal osteomyelitis and arthritis in children . ACDC . 1991;145:70–74
  18. Waldvogel FA , Medoff G , Swartz MN . Osteomyelitis: a review of clinical features, therapeutic considerations and unusual aspects (part 1) . N Engl J Med . 1970;282:198–205
  19. Fernandez M , Clark L , Baker A & Baker CJ . Discitis and vertebral osteomyelitis in children: an 18-year review . Pediatrics . 2000;105:1299–1304
  20. Highland TR , LaMont RL . Osteomyelitis of the pelvis in children . J Bone Joint Surg Am . 1983;65:230–234
  21. Wang CH , Huang FY . Septic arthritis in early infancy . Acta Paed Sin . 1990;31:69–75
  22. Wang CL , Wang SM , Yang YJ , et al.   Septic arthritis in children: relationship of causative pathogens, complications, and outcome . L Microbio Immunol Infect . 2003;36:41–46
  23. Ullodo-Gutierrez R , Avila-Aguero ML , Herrera ML , et al.   Invasive pneumococcal disease in Cost Rican children: a seven-year survey . Pediatr Infect Dis J . 2003;22:1069–1074
  24. Poyanli A , Poyanli O , Akan K , Sencer S . Pneumococcal vertebral osteomyelitis . Spine . 2001;26:2397–2399
  25. Dormans JP , Drummond DS . Pediatric hematogenous osteomyelitis: new trends in presentation, diagnosis, and treatment . J Am Acad Orthop Surg . 1994;2:333–341
  26. Gottsegen DN . Pneumococcal osteomyelitis associated with IgG2 subclass deficiency . Pediatr Infect Dis J . 1987;6:281–284
  27. Dagan R , Englehard D , Piccard E , et al.   Epidemiology of invasive childhood pneumococcal infections in Israel . JAMA . 1992;268:3328–3332
  28. Kaplan SL , Mason EO , Barson WJ , Wald ER , et al.   Three-year multicenter surveillance of systemic pneumococcal infections in children . Pediatrics . 1998;102:538–545
  29. Oliker R , Cunha B . Streptococcus pneumoniae septic arthritis and osteomyelitis in an HIV-seropositive patient . Heart & lung . 1999;28:74–76
  30. Hadari I , Dagan R , Gedalia A , Jeanine N , Moses S . Pneumococcal osteomyelitis, an unusual cluster of cases . Clin Pediatr . 1985;24:43–45
  31. Gold R . Diagnosis of osteomyelitis . Pediatr Rev . 1991;12:292–297
  32. Sonnen GM , Henry NK . Pediatric bone and join infections. Diagnosis and antimicrobial management . Pediatric Clin North Am . 1996;43:933–947
  33. Chemlal K , Trouillet JL , Carbon C , Yeni P . Vertebral osteomyelitis and meningitis due to a penicillin-resistant pneumococcal strain . Eur J Clin Microbiol Infect Dis . 1996;15:893–895

PII: S1875-9572(09)60020-6

doi:10.1016/S1875-9572(09)60020-6

Pediatrics & Neonatology
Volume 49, Issue 6 , Pages 248-253, December 2008