Pediatrics & Neonatology
Volume 50, Issue 2 , Pages 70-73, April 2009

Hypernatremic Dehydration Due to Concentrated Infant Formula: Report of Two Cases

  • Cheung Leung

      Affiliations

    • Division of Neonatology, Department of Pediatrics, Far Eastern Memorial Hospital, Panchiao, Taiwan, ROC
  • ,
  • Wen-Cheng Chang

      Affiliations

    • Department of Pediatrics, Far Eastern Memorial Hospital, Panchiao, Taiwan, ROC
    • Corresponding Author InformationCorresponding author. Division of Neonatology, Department of Pediatrics, Far Eastern Memorial Hospital, 21 Section 2, Na-Ya South Road, Panchiao, Taipei County, Taiwan
  • ,
  • Shu-Jen Yeh

      Affiliations

    • Department of Pediatrics, Far Eastern Memorial Hospital, Panchiao, Taiwan, ROC

Received 1 April 2008; received in revised form 16 October 2008; accepted 23 October 2008.

Article Outline

Hypernatremic dehydration is a rare but serious clinical condition in newborns and small infants. It is usually caused by diarrhea, improperly prepared infant formula, decreased fluid intake, or exclusive breastfeeding. Symptoms are usually masked until neurological symptoms occur. We report two infants who presented with fever and hypernatremic dehydration caused by concentrating infant formula to alleviate symptoms of constipation, and careless formula preparation due to confusion over spoon sizes, respectively. In the first case, status epilepticus occurred during early treatment, despite close serum sodium monitoring, though the infant was asymptomatic and thriving 4 years after discharge, with no identified neurodevelopmental deficits. The course of treatment was smooth in the second case, and no neurological complications developed. The practice of concentrating infant formula to relieve symptoms of constipation, although temporarily effective, is hazardous to newborns or young infants and can cause hypernatremic dehydration. Spoon sizes supplied with commercial infant formulas (30 mL/spoonful or 60 mL/spoonful) should be unified to avoid mistakes during preparation, especially by inexperienced and teenage mothers.

Key Words:  dehydration , hypernatremia , newborn

No full text is available. To read the body of this article, please view the PDF online.

 

Back to Article Outline

References 

  1. Yildizdas H Y , Satar M , Tutak E , et al.   May the best friend be an enemy if not recognized early: hypernatremic dehydration due to breastfeeding . Pediatr Emerg Care . 2005;21:445–448
  2. Van Amerongen RH , Moretta AC , Gaeta TJ . Severe hyper-natremic dehydration and death in a breast-fed infant . Pediatr Emerg Care . 2001;17:175–180
  3. Prakasam E , Rosenfeld WN . Hypernatremic dehydration in breast fed infants: diagnostic enigma because of the variable presentation . Pediatr Res . 1999;45:289A
  4. Laing IA , Wong CM . Hypernatremia in the first few days: is the incidence increasing? . Arch Dis Child . 2002;87:F158–F162
  5. Neifert MR . Prevention of breastfeeding tragedies . Pediatr Clin North Am . 2001;48:273–297
  6. Livingstone VH , Willis CE , Abdel-Wareth LO . Neonatal hyper-natremic dehydration associated with breast-feeding malnutrition: a retrospective survey . Can Med Assoc J . 2000;162:647–652
  7. Ergenekon W , Unal S , Gucuyener K , et al.   Hypernatremic dehydration in the newborn period and long-term follow up . Pediatr Int . 2007;49:19–23
  8. Manganaro R , Mami C , Marrone T , et al.   Incidence of dehydration and hypernatremia in exclusively breast-fed infants . J Pediatr . 2001;139:673–675
  9. American Academy of Pediatrics Work Group on Breastfeeding  . Breastfeeding and the use of human milk . Pediatrics . 1997;100:1035–1039
  10. Gebara BM , Everett KO . Dural sinus thrombosis complicating hypernatremic dehydration in a breastfed neonate . Clin Pediatr . 2001;40:45–48
  11. Mandell F , Fellers F . Hyperglycemia in hypernatremic dehydration . Clin Pediatr . 1974;13:367–369

PII: S1875-9572(09)60036-X

doi:10.1016/S1875-9572(09)60036-X

Pediatrics & Neonatology
Volume 50, Issue 2 , Pages 70-73, April 2009