Pediatrics & Neonatology
Volume 50, Issue 3 , Pages 110-116 , June 2009

Effect of Blood Transfusions on the Outcome of Very Low Body Weight Preterm Infants under Two Different Transfusion Criteria

  • Hsiu-Lin Chen

      Affiliations

    • Department of Pediatrics, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan
    • ,
  • Hsing-I Tseng

      Affiliations

    • Department of Pediatrics, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan
    • ,
  • Chu-Chong Lu

      Affiliations

    • Department of Pediatrics, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan
    • ,
  • San-Nan Yang

      Affiliations

    • Department of Pediatrics, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan
    • ,
  • Hui-Chen Fan

      Affiliations

    • Department of Nursing, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan
    • ,
  • Rei-Cheng Yang

      Affiliations

    • Department of Pediatrics, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan
    • Corresponding Author InformationCorresponding author. Department of Pediatrics, Kaohsiung Medical University Hospital, Kaohsiung Medical University, No. 100, Tzyou 1st Road, San Ming District, Kaohsiung 807, Taiwan

Received 2 January 2008 ,Revised 24 October 2008 ,Accepted 18 November 2008.

References 

  1. Strauss RG . Practical issues in neonatal transfusion practice . Am J Clin Pathol . 1997;107:S57–S63
  2. Bain A , Blackburn S . Issues in transfusing preterm infants in the NICU . J Perinat Neonatal Nurs . 2004;18:170–182
  3. Gibson BE , Todd A , Roberts I , et al.   Transfusion guidelines for neonates and older children . Br J Haematol . 2004;124:433–453
  4. Ohls RK . The use of erythropoietin in neonates . Clin Perinatol . 2000;27:681–696
  5. Ohls RK . Erythropoietin treatment in extremely low birth weight infants: blood in versus blood out . J Pediatr . 2002;141:3–6
  6. Dani C , Pezzati M , Martelli E , Prussi C , Bertini G , Rubaltelli FF . Effect of blood transfusions on cerebral haemodynamics in preterm infants . Acta Paediatr . 2002;91:938–941
  7. Cooke RW , Drury JA , Yoxall CW , James C . Blood transfusion and chronic lung disease in preterm infants . Eur J Pediatr . 1997;156:47–50
  8. Saugstad OD . Bronchopulmonary dysplasia-oxidative stress and antioxidants . Semin Neonatol . 2003;8:39–49
  9. Englert JA , Saunders RA , Purohit D , Hulsey TC , Ebeling M . The effect of anemia on retinopathy of prematurity in extremely low birth weight infants . J Perinatol . 2001;21:21–26
  10. Wheatley CM , Dickinson JL , Mackey DA , Craig JE , Sale MM . Retinopathy of prematurity: recent advances in our understanding . Arch Dis Child Fetal Neonatal Ed . 2002;87:F78–F82
  11. Hirano K , Morinobu T , Kim H , et al.   Blood transfusion increases radical promoting non-transferrin bound iron in preterm infants . Arch Dis Child Fetal Neonatal Ed . 2001;84:F188–F193
  12. Kabra NS , Kirpalani H . Blood transfusions in the premature nursery . Indian Pediatr . 2002;39:619–624
  13. Wardle SP , Drury J , Garr R , Weindling AM . Effect of blood transfusion on lipid peroxidation in preterm infants . Arch Dis Child Fetal Neonatal Ed . 2002;86:F46–F48
  14. Ringer SA , Richardson DK , Sacher RA , Keszler M , Churchill WH . Variations in transfusion practice in neonatal intensive care . Pediatrics . 1998;101:194–200
  15. Murray NA , Roberts IA . Neonatal transfusion practice . Arch Dis Child Fetal Neonatal Ed . 2004;89:F101–F107
  16. Bell EF , Strauss RG , Widness JA , et al.   Randomized trial of liberal versus restrictive guidelines for red blood cell transfusion in preterm infants . Pediatrics . 2005;115:1685–1691
  17. Stute H , Greiner B , Linderkamp O . Effect of blood transfusion on cardiorespiratory abnormalities in preterm infants . Arch Dis Child Fetal Neonatal Ed . 1995;72:F194–F196
  18. Poets CF , Pauls U , Bohnhorst B . Effect of blood transfusion on apnoea, bradycardia and hypoxaemia in preterm infants . Eur J Pediatr . 1997;156:311–316
  19. Westkamp E , Soditt V , Adrian S , Bohnhorst B , Groneck P , Poets CF . Blood transfusion in anemic infants with apnea of prematurity . Biol Neonate . 2002;82:228–232
  20. Ohls RK , Ehrenkranz RA , Wright LL , et al.   Effects of early erythropoietin therapy on the transfusion requirements of preterm infants below 1250 grams birth weight: a multicenter, randomized, controlled trial . Pediatrics . 2001;108:934–942
  21. Widness JA , Seward VJ , Kromer IJ , Burmeister LF , Bell EF , Strauss RG . Changing patterns of red blood cell transfusion in very low birth weight infants . J Pediatr . 1996;129:680–687
  22. Maier RF , Sonntag J , Walka MM , Liu G , Metze BC , Obladen M . Changing practices of red blood cell transfusions in infants with birth weights less than 1000 g . J Pediatr . 2000;136:220–224
  23. Swamy RS , Embleton ND . Red blood cell transfusions in preterm infants: is there a difference between restrictive and liberal criteria? . Pediatrics . 2006;117:257–258 author reply 258–9
  24. Murray N , Roberts I , Stanworth S . Red blood cell transfusion in neonates . Pediatrics . 2005;116:1609; author reply 1609–10.
  25. Boedy RF , Mathew OP . Randomized trial of liberal versus restrictive guidelines for red blood cell transfusion in preterm infants . Pediatrics . 2005;116:1048–1049 author reply 1049–50.
  26. Bell EF . Transfusion thresholds for preterm infants: how low should we go? . J Pediatr . 2006;149:287–289
  27. Bancalari E . Pathophysiology of bronchopulmonary dysplasia . In:  Polin RA ,  Fox WW ,  Abman SH editor. Fetal and neonatal physiology . Philadelphia: Saunders; 2004;p. 954–961

 This study was supported by a grant from the Premature Baby Foundation of Taiwan (Grant no. 9501).

PII: S1875-9572(09)60045-0

doi: 10.1016/S1875-9572(09)60045-0

Pediatrics & Neonatology
Volume 50, Issue 3 , Pages 110-116 , June 2009

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