Pediatrics & Neonatology
Volume 50, Issue 4 , Pages 147-151 , August 2009

Changing Clinical Presentations and Survival Pattern in Trisomy 18

  • Chien-Chou Hsiao

      Affiliations

    • Department of Pediatrics, Children's Hospital, Changhua Christian Hospital, Taiwan
    • Institute of Medical Research, College of Health Sciences, Chang Jung Christian University, Taiwan
    • Corresponding Author InformationCorresponding author. Department of Pediatrics, Children's Hospital, Changhua Christian Hospital, 135 Nan-Siau Street, Changhua City, 500 Taiwan
    • ,
  • Lon-Yen Tsao

      Affiliations

    • Department of Pediatrics, Children's Hospital, Changhua Christian Hospital, Taiwan
    • ,
  • Hsiao-Neng Chen

      Affiliations

    • Department of Pediatrics, Children's Hospital, Changhua Christian Hospital, Taiwan
    • ,
  • Han-Yao Chiu

      Affiliations

    • Department of Pediatrics, Children's Hospital, Changhua Christian Hospital, Taiwan
    • ,
  • Weng-Cheng Chang

      Affiliations

    • Institute of Medical Research, College of Health Sciences, Chang Jung Christian University, Taiwan

Received 20 August 2006 ,Revised 15 December 2008 ,Accepted 28 December 2008.

References 

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  2. Root S , Carey JC . Survival in trisomy 18 . Am J Med Genet . 1994;49:170–174
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  4. Edwards J , Harnden DG , Cameron AH , et al.   A new trisomic syndrome . Lancet . 1960;1:87–90
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  12. Kosho T , Nakamura T , Kawame H , et al.   Neonatal management of trisomy 18: clinical details of 24 patients receiving intensive treatment . Am J Med Genet Part A . 2006;140A:937–944
  13. Tanigawa T , Nakayama D , Miura K , et al.   Prenatal ultrasonographic findings may be useful in predicting the prognosis of trisomy 18 . Prenat Diagn . 2007;27:1039–1044
  14. Kalousek D , Barrott I , McGillivray B . Placental mosaicism and intrauterine survival of trisomy 13 and 18 . Am J Hum Genet . 1989;44:338–343
  15. Khoury MJ , Erickson JD , Cordero JF , et al.   Congenital malformations and intrauterine growth retardation: a population study . Pediatrics . 1988;82:83–90
  16. Hook EB , Cross PK , Schreinemachers DM . Chromosomal abnormality rates at amniocentesis and in live-born infants . JAMA . 1983;249:2034–2038
  17. Yamanaka M , Setoyama T , Igarashi Y , et al.   Pregnancy outcome of fetuses with trisomy 18 identified by prenatal sonography and chromosomal analysis in a perinatal center . Am J Med Genet Part A . 2006;140A:177–182

PII: S1875-9572(09)60053-X

doi: 10.1016/S1875-9572(09)60053-X

Pediatrics & Neonatology
Volume 50, Issue 4 , Pages 147-151 , August 2009

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