Pediatrics & Neonatology
Volume 50, Issue 6 , Pages 280-286, December 2009

Importance of Prevention and Early Intervention of Adverse Events in Pediatric Cardiac Catheterization: A Review of Three Years of Experience

  • Yu-Chih Huang

      Affiliations

    • Division of Pediatric Cardiology, Department of Pediatrics, China Medical University Hospital, Taichung, Taiwan
  • ,
  • Jeng-Sheng Chang

      Affiliations

    • Division of Pediatric Cardiology, Department of Pediatrics, China Medical University Hospital, Taichung, Taiwan
    • Corresponding Author InformationCorresponding author. Division of Pediatric Cardiology, Department of Pediatrics, China Medical University Hospital, 2 Yuh-Der Road, Taichung 40443, Taiwan
  • ,
  • Yung-Chang Lai

      Affiliations

    • Division of Pediatric Cardiology, Department of Pediatrics, China Medical University Hospital, Taichung, Taiwan
  • ,
  • Ping-Chun Li

      Affiliations

    • Division of Cardiovascular Surgery, Department of Surgery, China Medical University Hospital, Taichung, Taiwan

Received 5 August 2008; received in revised form 24 June 2009; accepted 26 June 2009.

Article Outline

Background

In spite of advances in many noninvasive instruments for studying cardiac anomalies in children, cardiac catheterization (CC) is still an essential method for the precise calculation of cardiovascular hemodynamic status and for performing therapeutic interventions. Accordingly, all adverse events (AE) related to CC are a major concern to pediatric cardiologists.

Patients and Methods

A total of 220 children with congenital heart disease (CHD) who received cardiac catheterization in our tertiary care hospital between the period of January 2000 and December 2002 were studied. One hundred and thirty-eight patients were non-cyanotic CHD, 71 were cyanotic CHD and 11 were complex CHD. Diagnostic CC was performed in 138 patients and therapeutic CC in 82 patients. All AEs that occurred during the CC procedures were identified, recorded and managed at the scene. The severities of AE were further classified into minor, obvious and severe.

Results

AEs were observed in 41 patients, including 22 (10%) minor, 16 (7.27%) obvious and 3 (1.36%) severe AEs. The three severe AEs were cardiac tamponade, severe ventricular tachycardia and marked hypoxia-and-bradycardia. None of the patients died. Therapeutic CC did not present a higher incidence of AE occurrence than diagnostic CC. However, a young age (p< 0.0001), low body weight (p< 0.0001) and cyanotic or complex CHD (p= 0.01) appeared to be risk factors for obvious and severe AE.

Conclusion

Although the complication of severe AE during CC may not be totally preventable, it is important to be aware of every early sign of AE and to initiate an effective intervention by a well trained resuscitation team.

Key Words:  adverse event , cardiac catheterization , complication , interventional catheterization , pediatrics

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References 

  1. Cohn HE , Freed MD , Hellenbrand WF , Fyler DC . Complications and mortality associated with cardiac catheterization in infants under one year: a prospective study . Pediatr Cardiol . 1985;6:123–131
  2. Zeevi B , Berant M , Fogelman R , Galit BM , Blieden LC . Acute complications in the current era of therapeutic cardiac catheterization for congential heart disease . Cardiol Young . 1999;9:266–272
  3. Stanger P , Heymann MA , Tarnoff H , Hoffman JIE , Rudolf AM . Complications of cardiac catheterization of neonates, infants, and children: a three-year study . Circulation . 1974;50:596–608
  4. De Bono D . Complications of diagnostic cardiac catheterization: results from 34,041 patients in the United Kingdom confidential enquiry into cardiac complications: the Joint Audit Committee of the British Cardiac Society and Royal College of Physicains of London . Br Heart J . 1993;70:297–330
  5. Mehta R , Lee KJ , Chaturvedi R , Benson L . Complications of pediatric cardiac catheterization: a review in the current era . Catheter Cardiovasc Interv . 2008;72:278–285
  6. Bennett D , Marcus R , Stokes M . Incidents and complications during pediatric cardiac catheterization . Paediatr Anaesth . 2005;15:1083–1088
  7. Tay CL , Tan GM , Ng SB . Critical incidents in paediatric anaesthesia: an audit of 10,000 anaesthetics in Singapore . Paediatr Anaesth . 2001;11:711–718
  8. Vitiello R , McCrindle BW , Nykanen D , Freedom RM , Benson LN . Complications associated with pediatric cardiac catheterization . J Am Coll Cardiol . 1998;32:1433–1440
  9. Cassidy SC , Schmidt KG , Van Hare GF , Stanger P , Teitel DF . Complications of pediatric cardiac catheterization: a 3-year study . J Am Coll Cardiol . 1992;19:1285–1293
  10. Huggon IC , Qureshi SA , Reidy J , Dos Anjos R , Baker EJ , Tynan M . Percutaneous transcatheter retrieval of misplaced therapeutic embolization devices . Br Heart J . 1994;72:470–475
  11. Silka MJ . Complications of interventional catheterization procedures in congenital heart disease . In:  Kron J ,  Morton MJ editor. Complications of Cardiac Catheterization and Angiography . New York: Futura Publishing Co; 1989;p. 203–225
  12. Herbert EC , Michael DF , Willianm FH . Complications and mortality associated with cardiac cathe terization in infants under one year: a prospective study . Pediatric Cardiology . 1985;6:123–131
  13. Steven CC , Klaus GS . Compli cations of pediatric cardiac catheterization: a 3-year study . J Am Coll Cardiol . 1992;19:1285–1293
  14. Rabinovitch M . Pathophysiology of pulmonary hypertension . In:  Allen HD ,  Gutgesell HP ,  Clark EB , et al. editor. Moss and Adams' Heart Disease in Infants, Children and Adolescents Including the Fetus and Young Adult . 6th edition. Philadelphia: Lippincott Williams and Wilkins; 2001;p. 1317–1320
  15. Atsumi N , Gomi S , Kanemoto S , et al.   Management of postoperative pulmonary hypertensive crisis in children-indication and usefulness of inhaled nitric oxide therapy as a pulmonary vasodilator . Nippon Kyobu Geka Gakkai Zasshi . 1996 Dec;44:2123–2129 [In Japanese]
  16. Didier J , Philippe P , Philippe M , Thierry M , Paseal V , Denis S . Inhaled nitric oxide as a therapy for pulmonary hypertension after operations for congenital heart defects . J Thorac Cardiovasc Surg . 1994;107:1129–1135
  17. Hopkins R , Bull C , Haworth S , de Leval MR , Stark J . Pulmonary hypertensive crises following surgery for congenital heart defects in young children . Eur J Cardiothorac Surg . 1991;5:628–634
  18. Wheller J , George B , Muller D , Jarmakani J . Diagnosis and management of postoperative pulmonary hypertensive crisis . Circulation . 1980;60:1640–1644
  19. Wessel DL , Keane JF , Fellows KE , et al.   Fibrinolytic therapy for femoral arterial thrombosis following cardiac catheterization in infants and children . Am J Cardiol . 1986;58:347–351
  20. Michael DF , Johx FK , Amxox R . The use of heparinization to prevent arterial thrombosis after percutaneous cardiac catheterization in children . Circulation . 1974;50:565–569

PII: S1875-9572(09)60078-4

doi:10.1016/S1875-9572(09)60078-4

Pediatrics & Neonatology
Volume 50, Issue 6 , Pages 280-286, December 2009