Pediatrics & Neonatology
Volume 51, Issue 1 , Pages 31-36 , February 2010

Effects of Budesonide and Fluticasone Propionate in Pediatric Asthma Patients

  • Lin-Yu Kuo

      Affiliations

    • Department of Pediatrics, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan
  • ,
  • Chih-Hsing Hung

      Affiliations

    • Department of Pediatrics, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan
    • Department of Pediatrics, Faculty of Pediatrics, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
    • Graduate Institute of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
  • ,
  • Hsing-I Tseng

      Affiliations

    • Department of Pediatrics, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan
  • ,
  • Jiunn-Ren Wu

      Affiliations

    • Department of Pediatrics, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan
    • Department of Pediatrics, Kaohsiung Municipal Hsiao-Kang Hospital, Kaohsiung, Taiwan
  • ,
  • Yuh-Jyh Jong

      Affiliations

    • Department of Pediatrics, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan
    • Department of Pediatrics, Faculty of Pediatrics, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
    • Graduate Institute of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
  • ,
  • Yu-Te Chu

      Affiliations

    • Department of Pediatrics, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan
    • Corresponding Author InformationCorresponding author. Department of Pediatrics, Kaohsiung Medical University Hospital, 100 Tz-You 1st Road, Kaohsiung 807, Taiwan

Received 7 March 2009 ,Revised 9 June 2009 ,Accepted 15 June 2009.

References 

  1. Barnes PJ , Chung KF , Page CP . Inflammatory mediators of asthma: an update . Pharmacol Rev . 1998;50:515–596
  2. Thomas PS . Tumour necrosis factor-alpha: the role of this multifunctional cytokine in asthma . Immunol Cell Biol . 2001;79:132–140
  3. Kips JC . Cytokines in asthma . Eur Respir J Suppl . 2001;34:24s–33s
  4. Bochner BS , Hudson SA , Xiao HQ , Liu MC . Release of both CCR4-active and CXCR3-active chemokines during human allergic pulmonary late-phase reactions . J Allergy Clin Immunol . 2003;112:930–934
  5. Liu L , Jarjour NN , Busse WW , Kelly EA . Enhanced generation of helper T type 1 and 2 chemokines in allergen-induced asthma . Am J Respir Crit Care Med . 2004;169:1118–1124
  6. Hung CH , Li CY , Lai YS , Hsu PC , Hua YM , Yang KD . Discrepant clinical responses and blood chemokine profiles between two non-steroidal anti-inflammatory medications for children with mild persistent asthma . Pediatr Allergy Immunol . 2005;16:306–309
  7. Leung TF , Wong CK , Lam CWK , et al.   Plasma TARC concentration may be a useful marker for asthmatic exacerbation in children . Eur Respir J . 2003;21:616–620
  8. Imai T , Baba M , Nishimura M , Kakizaki M , Takagi S , Yoshie O . The T cell-directed CC chemokine TARC is a highly specific biological ligand for CC chemokine receptor 4 . J Biol Chem . 1997;272:15036–15042
  9. Liu AH , Zeiger R , Sorkness C , et al.   Development and cross-sectional validation of the Childhood Asthma Control Test . J Allergy Clin Immunol . 2007;119:817–825
  10. Schatz M , Sorkness CA , Li JT , et al.   Asthma Control Test: reliability, validity, and responsiveness in patients not previously followed by asthma specialists . J Allergy Clin Immunol . 2006;117:549–556
  11. Global Initiative for Asthma. Global strategy for asthma management and prevention. In: National Institutes of Health. National Heart, Lung, and Blood Institute, 2008. Available at: http://www.ginasthma.com/ [Date accessed: December 20, 2008]
  12. Juniper EF , Kline PA , Vanzieleghem MA , Ramsdale EH , O'Byrne PM , Hargreave FE . Effect of long-term treatment with an inhaled corticosteroid (budesonide) on airway hyperresponsiveness and clinical asthma in nonsteroid-dependent asthmatics . Am Rev Respir Dis . 1990;142:832–836
  13. National Institutes of Health  . Expert panel report 3: guidelines for the diagnosis and management of asthma . Available at: http://www.nhlbi.nih.gov/guidelines/asthma/asthgdln.pdf [Date accessed: December 20, 2008]
  14. Khor YH , Feltis BN , Reid DW , et al.   Airway cell and cytokine changes in early asthma deterioration after inhaled corticosteroid reduction . Clin Exp Allergy . 2007;37:1189–1198
  15. Nathan RA , Sorkness CA , Kosinski M , et al.   Development of the asthma control test: a survey for assessing asthma control . J Allergy Clin Immunol . 2004;113:59–65
  16. Burke C , Power CK , Norris A , Condez A , Schmekel B , Poulter LW . Lung function and immunopathological changes after inhaled corticosteroid therapy in asthma . Eur Respir J . 1992;5:73–79
  17. Burke CM , Sreenan S , Power CK , Pathmakanthan S , Poulter LW . Mechanism of action of inhaled corticosteroids in bronchial asthma: a controlled study . Eur Respir J . 1994;7:421S; [Abstract]
  18. Barnes PJ . Molecular mechanisms of glucocorticoid action in asthma . Pulm Pharmacol Ther . 1997;10:3–19
  19. Rizzo MC , Sole D . Inhaled corticosteroids in the treatment of respiratory allergy: safety vs. efficacy . J Pediatr (Rio J) . 2006;82:S198–S205
  20. Panina-Bordignon P , Papi A , Mariani M , et al.   The C-C chemokine receptors CCR4 and CCR8 identify airway T cells of allergen-challenged atopic asthmatics . J Clin Invest . 2001;107:1357–1364
  21. Lai ST , Hung CH , Hua YM , Hsu SH , Jong YJ , Suen JL . T-helper 1-related chemokines in the exacerbation of childhood asthma . Pediatr Int . 2008;50:99–102
  22. Kips JC , Tavernier JH , Joos GF , Peleman RA , Pauwels RA . The potential role of tumour necrosis factor alpha in asthma . Clin Exp Allergy . 1993;23:247–250
  23. Kharitonov SA , Barnes PJ . Exhaled biomarkers . Chest . 2006;130:1541–1546
  24. Pijnenburg MW , De Jongste JC . Exhaled nitric oxide in childhood asthma: a review . Clin Exp Allergy . 2008;38:246–259
  25. Adams N , Lasserson TJ , Cates CJ , Jones PW . Fluticasone versus beclomethasone or budesonide for chronic asthma in adults and children . Cochrane Database Syst Rev . 2007; CD002310.
  26. Yang JZ , Young AL , Chiang PC , Thurston A , Pretzer DK . Fluticasone and budesonide nanosuspensions for pulmonary delivery: preparation, characterization, and pharmacokinetic studies . J Pharm Sci . 2008;97:4869–4878

PII: S1875-9572(10)60007-1

doi: 10.1016/S1875-9572(10)60007-1

Pediatrics & Neonatology
Volume 51, Issue 1 , Pages 31-36 , February 2010