Pediatrics & Neonatology
Volume 51, Issue 4 , Pages 214-218, August 2010

Effects of Flow Rate on Delivery of Bubble Continuous Positive Airway Pressure in an In Vitro Model

  • Tsyr-Yuh Ho

      Affiliations

    • Division of Pediatrics, Zuoying Armed Forces General Hospital, Kaohsiung, Taiwan
  • ,
  • Shan-Fu Ou

      Affiliations

    • Division of Pediatrics, Zuoying Armed Forces General Hospital, Kaohsiung, Taiwan
  • ,
  • Shih-Hui Huang

      Affiliations

    • Department of Nursing, Fooying University, Kaohsiung County, Taiwan
  • ,
  • Chi-Ning Lee

      Affiliations

    • Division of Pediatrics, Zuoying Armed Forces General Hospital, Kaohsiung, Taiwan
  • ,
  • Luo-Ping Ger

      Affiliations

    • Department of Pediatrics and Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung, National Yang-Ming University, Taipei, Taiwan
  • ,
  • Kai-Sheng Hsieh

      Affiliations

    • Department of Pediatrics and Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung, National Yang-Ming University, Taipei, Taiwan
  • ,
  • Hui-Ying Cheng

      Affiliations

    • Department of Nursing, Zuoying Armed Forces General Hospital, Kaohsiung, Taiwan
  • ,
  • Wei Yang Lee

      Affiliations

    • Department of Pediatrics, Kaohsiung Municipal United Hospital, Kaohsiung, Taiwan
    • Corresponding Author InformationCorresponding authors. Department of Pediatrics, Kaohsiung Veterans General Hospital, 386 Ta-Chung 1st Road, Kaohsiung 813, Taiwan, or Department of Pediatrics, Kaohsiung Municipal United Hospital, 976 Chunghwa 1st Road, Kaohsiung 804, Taiwan. E-mail: treeho@yahoo.com.tw
  • ,
  • Ken-Pen Weng

      Affiliations

    • Division of Pediatrics, Zuoying Armed Forces General Hospital, Kaohsiung, Taiwan
    • Department of Nursing, Fooying University, Kaohsiung County, Taiwan
    • Department of Pediatrics and Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung, National Yang-Ming University, Taipei, Taiwan
    • Yuh-Ing Junior College of Health Care and Management, Kaohsiung, Taiwan
    • Corresponding Author InformationCorresponding authors. Department of Pediatrics, Kaohsiung Veterans General Hospital, 386 Ta-Chung 1st Road, Kaohsiung 813, Taiwan, or Department of Pediatrics, Kaohsiung Municipal United Hospital, 976 Chunghwa 1st Road, Kaohsiung 804, Taiwan. E-mail: treeho@yahoo.com.tw

Received 23 June 2009; received in revised form 23 October 2009; accepted 16 November 2009.

Article Outline

Background

There has been concern over the effect of vigorous bubbling on the delivery pressure during the operation of the bubble nasal continuous positive airway pressure (CPAP) system. We investigated the relationship between intra-tubing pressure changes and flow rates in a closed bubble CPAP system in vitro.

Methods

Using an experimental (in vitro) model, the distal connecting tube of the CPAP system was immersed under the water seal to a depth of 5 cm. Sixteen different flow rates, ranging from 2 L/min to 20 L/min, were tested. The procedure was repeated 10 times at each flow rate, and the intra-tubing pressure was recorded.

Results

The intra-tubing pressure within the model increased as the air flow rates were adjusted from 2 L/min to 20 L/min. The relationship was represented by the following equation, pressure (cmH2O) = 5.37 + 0.15 × flow rate (L/min) (R2 = 0.826, p < 0.001).

Conclusion

These results demonstrated that the intra-tubing pressure in a bubble CPAP system was highly correlated with flow rate in vitro.

Key Words:  bubble CPAP , flow , pressure

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PII: S1875-9572(10)60041-1

doi:10.1016/S1875-9572(10)60041-1

Pediatrics & Neonatology
Volume 51, Issue 4 , Pages 214-218, August 2010