Pediatrics & Neonatology
Volume 51, Issue 4 , Pages 227-234, August 2010

Role of Multi-slice and Three-dimensional Computed Tomography in Delineating Extracardiac Vascular Abnormalities in Neonates

  • Yew Giin Long

      Affiliations

    • Department of Pediatrics, Sin Lau Hospital, Madou, Taiwan
  • ,
  • Yeng-Ying Yang

      Affiliations

    • Department of Pediatrics, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan
  • ,
  • I-Lun Huang

      Affiliations

    • Department of Radiology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan
  • ,
  • Jun-Yen Pan

      Affiliations

    • Department of Surgery, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan
  • ,
  • Ming-Ting Wu

      Affiliations

    • Department of Radiology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan
  • ,
  • Ken-Pen Weng

      Affiliations

    • Department of Pediatrics, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan
  • ,
  • Kai-Sheng Hsieh

      Affiliations

    • Department of Pediatrics, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan
    • Corresponding Author InformationCorresponding author. Department of Pediatrics, Kaohsiung Veterans General Hospital, 386 Ta-Chung 1st Road, Kaohsiung, 81346, Taiwan

Received 2 July 2009; received in revised form 22 October 2009; accepted 4 December 2009.

Article Outline

Background

Recent advances in multi-slice computed tomography (MSCT) and three-dimensional computed tomography (3D CT) provide good-resolution images and short scan time for complete diagnosis of congenital heart disease (CHD). In the present study, we found that MSCT rapidly provides clinically relevant information for diagnosing extracardiac vascular anatomy in neonates with CHD. It is less invasive, necessitating only minimum or no sedation and a relatively small amount of contrast material. These advantages are crucial, especially for critically ill neonates.

Methods

Between January 2007 and December 2008, MSCT scans were conducted on 41 neonates who were admitted to our neonatal intensive care unit. All the neonates were suspected to have complex CHD after an initial echocardiography examination. The scans were focused on detecting extracardiac vascular anatomy and abnormalities. All the image data sets were sent to image processing workstations for multiplanar interactive viewing and 3D reconstruction.

Results

High-resolution MSCT scan images were obtained from 41 patients. Reported indications and findings of extracardiac abnormalities and related structural anatomy pertaining to congenital heart disease from MSCT and 3D CT findings were confirmed by clinical and surgical findings by a team of multidisciplinary congenital heart disease specialists.

Conclusion

Based on clinical and surgical confirmation of the MSCT scan results from a multidisciplinary congenital heart disease specialist team, we concluded that adequate information on CHD, specifically that regarding extracardiac abnormalities of the anatomy, can be obtained and MSCT can be used to replace cardiac catheterization.

Key Words:  computed tomography , congenital heart disease , neonate

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References 

  1. Soongswang J , Nana A , Laohaprasitiporn D , et al.   Limitation of transthoracic echocardiography in the diagnosis of congenital heart diseases . J Med Assoc Thai . 2000;83(Suppl 2):S111–S117
  2. Gutgesell HP , Huhta JC , Latson LA , et al.   Accuracy of two-dimensional echocardiography in the diagnosis of congenital heart disease . Am J Cardiol . 1985;55:514–518
  3. Simpson JM , Moore P , Teitel DF . Cardiac catheterization of low birth weight infants . Am J Cardiol . 2001;87:1372–1377
  4. Vitiello R , McCrindle BW , Nykanen D , et al.   Complications associated with pediatric cardiac catheterization . J Am Coll Cardiol . 1998;32:1433–1440
  5. Sjirk JW , Jennifer AH , Juan CA , et al.   Three-dimensional helical CT of pulmonary arteries in infants and children with congenital heart disease . AJR . 1999;173:109–111
  6. Teruhiro K , Masahiro I , Junichi T , et al.   Three-dimensional helical computed tomographic angiography in neonates and infants with complex congenital heart disease . Am Heart J . 2000;139:654–660
  7. Yasunobu H , Kazuhiro M , Tetsuya K , et al.   Accurate quantification of pulmonary artery diameter in patients with cyanotic congenital heart disease using multidetector-row computed tomography . Am Heart J . 2007;154:783–788
  8. Isao S , Yasutotoshi Y , Seiichiro O , et al.   Application of helical computed tomographic angiography with differential color imaging three-dimensional reconstruction in the diagnosis of complicated congenital heart diseases . J Thorac Cardiovasc Surg . 2003;125:36–39
  9. Cinar A , Haliloglu M , Karagoz T , et al.   Interrupted aortic arch in a neonate: multidetector CT diagnosis . Pediatr Radiol . 2004;34:901–903
  10. Bean MJ , Pannu H , Fishman EK . Three-dimensional computed tomographic imaging of complex congenital cardiovascular abnormalities . J Comput Assist Tomogr . 2005;29:721–724
  11. Samyn MM . A review of the complementary information available with cardiac magnetic resonance imaging and multi-slice computed tomography (CT) during the study of congenital heart disease . Int J Cardiovasc Imaging . 2004;20:569–578
  12. Sridhar PG , Kalyanpur A , Suresh PV , et al.   Total anomalous pulmonary venous connection: helical computed tomography as an alternative to angiography . Indian Heart J . 2003;55:624–627
  13. Eichhorn JG , Fink C , Long F , et al.   Multidetector CT for the diagnosis of congenital vascular anomalies and associated complications in newborns and infants . Rofo . 2005;177:1366–1372 [In German]
  14. Lee T , Tsai IC , Fu YC , et al.   Using multidetector-row CT in neonates with complex congenital heart disease to replace diagnostic cardiac catheterization for anatomical investigation: initial experiences in technical and clinical feasibility . Pediatr Radiol . 2006;36:1273–1282
  15. Gentles TL , Mayer JE , Gauvreau K , et al.   Fontan operation in five hundred consecutive patients: factors influencing early and late outcome . J Thorac Cardiovasc Surg . 1997;114:376–391
  16. Elzenga NJ , von Suylen RJ , Frohn-Mulder I , et al.   Juxtaductal pulmonary artery coarctation. An underestimated cause of branch pulmonary artery stenosis in patients with pulmonary atresia or stenosis and a ventricular septal defect . J Thorac Cardiovasc Surg . 1990;100:416–424
  17. Agnoletti G , Boudjemline Y , Bonnet D , et al.   Surgical reconstruction of occluded pulmonary arteries in patients with congenital heart disease: effects on pulmonary artery growth . Circulation . 2004;109:2314–2318
  18. Cochrane AD , Brizard CP , Penny DJ , et al.   Management of the univentricular connection: are we improving? . Eur J Cardiothorac Surg . 1997;12:107–115
  19. Manson O , Babyn P , Filler R , et al.   Three-dimensional imaging of the pediatric trachea in congenital tracheal stenosis . Pediatr Radiol . 1994;24:175–181
  20. Keller PJ , Drayer BP , Fram EK , et al.   MR angiography with two-dimensional acquisition and three-dimensional display . Radiology . 1992;173:527–532
  21. Simpson IA , Chung KJ , Glass RF , et al.   Magnetic resonance imaging for evaluation of anatomy and flow relations in infants and children with coarctation of the aorta . Circulation . 1988;78:142–148
  22. Hardy CE , Helton GJ , Kondo C , et al.   Usefulness of magnetic resonance imaging for evaluating great-vessel anatomy after arterial switch operation for D-transposition of the great arteries . Am Heart J . 1994;128:326–332
  23. Fogel MA , Donofrio MT , Ramacioti C , et al.   Magnetic resonance and echocordiographic imaging of pulmonary artery size throughout stages of Fontan reconstruction . Circulation . 1994;90:2927–2936
  24. Fawzy ME , Sinner WV , Rifai A , et al.   Magnetic resonance imaging compared with angiography in the evaluation of intermediate-term result of coarctation balloon angioplosty . Am Heart J . 1993;126:1380–1384
  25. Hirsch R , Kilner PJ , Connelly MS , et al.   Diagnosis in adolescents and adults with congenital heart disease: prospective assessment of individual and combined roles of magnetic resonance imaging and transesophageal echocardiography . Circulation . 1994;90:2937–2951
  26. Molinori G , Balbi M , Postorini G , et al.   Magnetic resonance imaging in Bland-White-Garland syndrome . Am Heart J . 1995;129:1040–1042
  27. Donofrio MT , Clark BJ , Ramaciotti C , et al.   Regional wall motion and strain of transplanted hearts in pediatric patients using magnetic resonance tagging . Am J Physiol . 1999;227(Suppl):R1481–R1487
  28. Bacher K , Bogaert E , Lapere R , et al.   Patient-specific dose and radiation risk estimation in pediatric cardiac catheterization . Circulation . 2005;111:83–89

PII: S1875-9572(10)60043-5

doi:10.1016/S1875-9572(10)60043-5

Pediatrics & Neonatology
Volume 51, Issue 4 , Pages 227-234, August 2010